Management of progressive pulmonary nodules found during and outside of CT lung cancer screening studies.
Identifieur interne : 000840 ( Main/Exploration ); précédent : 000839; suivant : 000841Management of progressive pulmonary nodules found during and outside of CT lung cancer screening studies.
Auteurs : Mathias Meyer [Allemagne] ; Rozemarijn Vliegenthart [Pays-Bas] ; Thomas Henzler [Allemagne] ; Daniel Buergy [Allemagne] ; Frank A. Giordano [Allemagne] ; Michael Kostrzewa [Allemagne] ; Nils Rathmann [Allemagne] ; Odd Terje Brustugun [Norvège] ; Lucio Crino ; Anne-Marie C. Dingemans [Pays-Bas] ; Michael Dusmet [Royaume-Uni] ; Dean Fennell [Royaume-Uni] ; Dominique Grunenwald [France] ; Rudolf Maria Huber [Allemagne] ; Marcin Moniuszko [Pologne] ; Francoise Mornex [France] ; Mauro Papotti [Italie] ; Lothar Pilz [Allemagne] ; Suresh Senan [Pays-Bas] ; Kostas Syrigos [Grèce] ; Maurice Pérol ; Jhanelle E. Gray [États-Unis] ; Christoph Schabel [Allemagne] ; Jan Van Meerbeeck [Belgique] ; Nico Van Zandwijk [Australie] ; Cai Cun Zhou [République populaire de Chine] ; Christian Manegold [Allemagne] ; Wieland Voigt [Allemagne] ; Eric Dominic Roessner [Allemagne]Source :
- Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [ 1556-1380 ] ; 2017.
Abstract
Although the effectiveness of screening for lung cancer remains controversial, it is a fact that the majority of lung cancers are diagnosed at an advanced stage outside of lung cancer screening programs. In 2013, the U.S. Preventive Services Task Force (USPSTF) revised its lung cancer screening recommendation, now supporting lung cancer screening by low-dose computed tomography (LDCT) in patients at high risk. This is also endorsed by many major medical societies and advocacy group stakeholders, however with different eligibility criteria. In Europe, population-based lung cancer screening has so far not been recommended or implemented, as some important issues remain unresolved. Among them remains the open question on how enlarging pulmonary nodules (PNs) detected in lung cancer screening should be managed. This article comprises two parts: a review of the current lung cancer screening approaches, as well as the potential therapeutic options for enlarging PNs, followed by a meeting report including consensus statements of an interdisciplinary expert panel that discussed the potential of the different therapeutic options during the Dresden 2015 Post World Congress of Lung Cancer (WCLC) - International Association for the Study of Lung Cancer (IASLC) meeting.
DOI: 10.1016/j.jtho.2017.09.1956
PubMed: 28962947
Affiliations:
- Allemagne, Australie, Belgique, France, Grèce, Italie, Norvège, Pays-Bas, Pologne, Royaume-Uni, République populaire de Chine, États-Unis
- Angleterre, Floride, Grand Londres, Groningue (province), Nouvelle-Galles du Sud, Piémont, Île-de-France
- Groningue (ville), Londres, Paris, Sydney, Turin
- Université de Groningue, Université de Sydney
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Dingemans</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pulmonology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pulmonology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre</wicri:regionArea><wicri:noRegion>Maastricht University Medical Centre</wicri:noRegion></affiliation></author><author><name sortKey="Dusmet, Michael" sort="Dusmet, Michael" uniqKey="Dusmet M" first="Michael" last="Dusmet">Michael Dusmet</name><affiliation wicri:level="3"><nlm:affiliation>The Royal Brompton Hospital, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Royal Brompton Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Fennell, Dean" sort="Fennell, Dean" uniqKey="Fennell D" first="Dean" last="Fennell">Dean Fennell</name><affiliation wicri:level="1"><nlm:affiliation>University Hospitals Leicester, Leicester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University Hospitals Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Grunenwald, Dominique" sort="Grunenwald, Dominique" uniqKey="Grunenwald D" first="Dominique" last="Grunenwald">Dominique Grunenwald</name><affiliation wicri:level="3"><nlm:affiliation>Department of Thoracic Surgery, Tenon Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Thoracic Surgery, Tenon Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Huber, Rudolf Maria" sort="Huber, Rudolf Maria" uniqKey="Huber R" first="Rudolf Maria" last="Huber">Rudolf Maria Huber</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Thoracic Oncology Centre Munich Ludwig Maximilians University, DZL (CPC-M) Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine, Thoracic Oncology Centre Munich Ludwig Maximilians University, DZL (CPC-M) Munich</wicri:regionArea><wicri:noRegion>DZL (CPC-M) Munich</wicri:noRegion><wicri:noRegion>DZL (CPC-M) Munich</wicri:noRegion><wicri:noRegion>DZL (CPC-M) Munich</wicri:noRegion></affiliation></author><author><name sortKey="Moniuszko, Marcin" sort="Moniuszko, Marcin" uniqKey="Moniuszko M" first="Marcin" last="Moniuszko">Marcin Moniuszko</name><affiliation wicri:level="1"><nlm:affiliation>Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Białystok, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Białystok</wicri:regionArea><wicri:noRegion>Białystok</wicri:noRegion></affiliation></author><author><name sortKey="Mornex, Francoise" sort="Mornex, Francoise" uniqKey="Mornex F" first="Francoise" last="Mornex">Francoise Mornex</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Centre Hospitalier Lyon Sud, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiation Oncology, Centre Hospitalier Lyon Sud</wicri:regionArea><wicri:noRegion>Centre Hospitalier Lyon Sud</wicri:noRegion><wicri:noRegion>Centre Hospitalier Lyon Sud</wicri:noRegion></affiliation></author><author><name sortKey="Papotti, Mauro" sort="Papotti, Mauro" uniqKey="Papotti M" first="Mauro" last="Papotti">Mauro Papotti</name><affiliation wicri:level="3"><nlm:affiliation>Department of Oncology, University of Turin, 10043, Turin, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Oncology, University of Turin, 10043, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Pilz, Lothar" sort="Pilz, Lothar" uniqKey="Pilz L" first="Lothar" last="Pilz">Lothar Pilz</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, University medical center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Biostatistics, University medical center Mannheim</wicri:regionArea><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Senan, Suresh" sort="Senan, Suresh" uniqKey="Senan S" first="Suresh" last="Senan">Suresh Senan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, VU University Medical Center Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Radiation Oncology, VU University Medical Center Amsterdam</wicri:regionArea><wicri:noRegion>VU University Medical Center Amsterdam</wicri:noRegion></affiliation></author><author><name sortKey="Syrigos, Kostas" sort="Syrigos, Kostas" uniqKey="Syrigos K" first="Kostas" last="Syrigos">Kostas Syrigos</name><affiliation wicri:level="1"><nlm:affiliation>Sotiria General Hospital, Athens School of Medicine, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Sotiria General Hospital, Athens School of Medicine</wicri:regionArea><wicri:noRegion>Athens School of Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Perol, Maurice" sort="Perol, Maurice" uniqKey="Perol M" first="Maurice" last="Pérol">Maurice Pérol</name><affiliation><nlm:affiliation>Department of Medical Oncology, Léon Bérard Cancer Center, Lyon France.</nlm:affiliation><wicri:noCountry code="subField">Lyon France</wicri:noCountry></affiliation></author><author><name sortKey="Gray, Jhanelle E" sort="Gray, Jhanelle E" uniqKey="Gray J" first="Jhanelle E" last="Gray">Jhanelle E. Gray</name><affiliation wicri:level="2"><nlm:affiliation>Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Schabel, Christoph" sort="Schabel, Christoph" uniqKey="Schabel C" first="Christoph" last="Schabel">Christoph Schabel</name><affiliation wicri:level="1"><nlm:affiliation>Department for Diagnostic and Interventional Radiology, Eberhard Karls University Tübingen, University Hospital Tübingen, 72076, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Diagnostic and Interventional Radiology, Eberhard Karls University Tübingen, University Hospital Tübingen, 72076, Tübingen</wicri:regionArea><wicri:noRegion>72076, Tübingen</wicri:noRegion><wicri:noRegion>72076, Tübingen</wicri:noRegion><wicri:noRegion>Tübingen</wicri:noRegion></affiliation></author><author><name sortKey="Van Meerbeeck, Jan" sort="Van Meerbeeck, Jan" uniqKey="Van Meerbeeck J" first="Jan" last="Van Meerbeeck">Jan Van Meerbeeck</name><affiliation wicri:level="1"><nlm:affiliation>Thoracic Oncology/MOCA, Antwerp University Hospital, Antwerp University, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Thoracic Oncology/MOCA, Antwerp University Hospital, Antwerp University</wicri:regionArea><wicri:noRegion>Antwerp University</wicri:noRegion></affiliation></author><author><name sortKey="Van Zandwijk, Nico" sort="Van Zandwijk, Nico" uniqKey="Van Zandwijk N" first="Nico" last="Van Zandwijk">Nico Van Zandwijk</name><affiliation wicri:level="4"><nlm:affiliation>Asbestos Diseases Research Institute, University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Asbestos Diseases Research Institute, University of Sydney, Sydney, New South Wales</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Zhou, Cai Cun" sort="Zhou, Cai Cun" uniqKey="Zhou C" first="Cai Cun" last="Zhou">Cai Cun Zhou</name><affiliation wicri:level="1"><nlm:affiliation>Department of Lung Cancer and Immunology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, People's Republic of China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Lung Cancer and Immunology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine</wicri:regionArea><wicri:noRegion>Tongji University School of Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Manegold, Christian" sort="Manegold, Christian" uniqKey="Manegold C" first="Christian" last="Manegold">Christian Manegold</name><affiliation wicri:level="1"><nlm:affiliation>Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University medical center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University medical center Mannheim</wicri:regionArea><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Voigt, Wieland" sort="Voigt, Wieland" uniqKey="Voigt W" first="Wieland" last="Voigt">Wieland Voigt</name><affiliation wicri:level="1"><nlm:affiliation>Medical Innovation and Management, Steinbeis University Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medical Innovation and Management, Steinbeis University Berlin</wicri:regionArea><wicri:noRegion>Steinbeis University Berlin</wicri:noRegion><wicri:noRegion>Steinbeis University Berlin</wicri:noRegion><wicri:noRegion>Steinbeis University Berlin</wicri:noRegion></affiliation></author><author><name sortKey="Roessner, Eric Dominic" sort="Roessner, Eric Dominic" uniqKey="Roessner E" first="Eric Dominic" last="Roessner">Eric Dominic Roessner</name><affiliation wicri:level="1"><nlm:affiliation>Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University medical center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University medical center Mannheim</wicri:regionArea><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date 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nodules found during and outside of CT lung cancer screening studies.</title><author><name sortKey="Meyer, Mathias" sort="Meyer, Mathias" uniqKey="Meyer M" first="Mathias" last="Meyer">Mathias Meyer</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Germany. Electronic address: mathias.meyer@medma.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim</wicri:regionArea><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Vliegenthart, Rozemarijn" sort="Vliegenthart, Rozemarijn" uniqKey="Vliegenthart R" first="Rozemarijn" last="Vliegenthart">Rozemarijn Vliegenthart</name><affiliation wicri:level="4"><nlm:affiliation>Center for Medical Imaging North-East Netherlands, University of Groningen, University Medical Center Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Center for Medical Imaging North-East Netherlands, University of Groningen, University Medical Center Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Henzler, Thomas" sort="Henzler, Thomas" uniqKey="Henzler T" first="Thomas" last="Henzler">Thomas Henzler</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim</wicri:regionArea><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Buergy, Daniel" sort="Buergy, Daniel" uniqKey="Buergy D" first="Daniel" last="Buergy">Daniel Buergy</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University Medical Center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, University Medical Center Mannheim</wicri:regionArea><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Giordano, Frank A" sort="Giordano, Frank A" uniqKey="Giordano F" first="Frank A" last="Giordano">Frank A. Giordano</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University Medical Center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, University Medical Center Mannheim</wicri:regionArea><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Kostrzewa, Michael" sort="Kostrzewa, Michael" uniqKey="Kostrzewa M" first="Michael" last="Kostrzewa">Michael Kostrzewa</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim</wicri:regionArea><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Rathmann, Nils" sort="Rathmann, Nils" uniqKey="Rathmann N" first="Nils" last="Rathmann">Nils Rathmann</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim</wicri:regionArea><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion><wicri:noRegion>University Medical Center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Brustugun, Odd Terje" sort="Brustugun, Odd Terje" uniqKey="Brustugun O" first="Odd Terje" last="Brustugun">Odd Terje Brustugun</name><affiliation wicri:level="1"><nlm:affiliation>Section of Oncology, Drammen hospital, Vestre Viken Hospital Trust, Drammen, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Section of Oncology, Drammen hospital, Vestre Viken Hospital Trust, Drammen</wicri:regionArea><wicri:noRegion>Drammen</wicri:noRegion></affiliation></author><author><name sortKey="Crino, Lucio" sort="Crino, Lucio" uniqKey="Crino L" first="Lucio" last="Crino">Lucio Crino</name><affiliation><nlm:affiliation>University Medical School of Perugia, Azienda Ospedale Perugia, Perugia.</nlm:affiliation><wicri:noCountry code="subField">Perugia</wicri:noCountry></affiliation></author><author><name sortKey="Dingemans, Anne Marie C" sort="Dingemans, Anne Marie C" uniqKey="Dingemans A" first="Anne-Marie C" last="Dingemans">Anne-Marie C. Dingemans</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pulmonology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pulmonology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre</wicri:regionArea><wicri:noRegion>Maastricht University Medical Centre</wicri:noRegion></affiliation></author><author><name sortKey="Dusmet, Michael" sort="Dusmet, Michael" uniqKey="Dusmet M" first="Michael" last="Dusmet">Michael Dusmet</name><affiliation wicri:level="3"><nlm:affiliation>The Royal Brompton Hospital, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Royal Brompton Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Fennell, Dean" sort="Fennell, Dean" uniqKey="Fennell D" first="Dean" last="Fennell">Dean Fennell</name><affiliation wicri:level="1"><nlm:affiliation>University Hospitals Leicester, Leicester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University Hospitals Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Grunenwald, Dominique" sort="Grunenwald, Dominique" uniqKey="Grunenwald D" first="Dominique" last="Grunenwald">Dominique Grunenwald</name><affiliation wicri:level="3"><nlm:affiliation>Department of Thoracic Surgery, Tenon Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Thoracic Surgery, Tenon Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Huber, Rudolf Maria" sort="Huber, Rudolf Maria" uniqKey="Huber R" first="Rudolf Maria" last="Huber">Rudolf Maria Huber</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Thoracic Oncology Centre Munich Ludwig Maximilians University, DZL (CPC-M) Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine, Thoracic Oncology Centre Munich Ludwig Maximilians University, DZL (CPC-M) Munich</wicri:regionArea><wicri:noRegion>DZL (CPC-M) Munich</wicri:noRegion><wicri:noRegion>DZL (CPC-M) Munich</wicri:noRegion><wicri:noRegion>DZL (CPC-M) Munich</wicri:noRegion></affiliation></author><author><name sortKey="Moniuszko, Marcin" sort="Moniuszko, Marcin" uniqKey="Moniuszko M" first="Marcin" last="Moniuszko">Marcin Moniuszko</name><affiliation wicri:level="1"><nlm:affiliation>Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Białystok, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Białystok</wicri:regionArea><wicri:noRegion>Białystok</wicri:noRegion></affiliation></author><author><name sortKey="Mornex, Francoise" sort="Mornex, Francoise" uniqKey="Mornex F" first="Francoise" last="Mornex">Francoise Mornex</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Centre Hospitalier Lyon Sud, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiation Oncology, Centre Hospitalier Lyon Sud</wicri:regionArea><wicri:noRegion>Centre Hospitalier Lyon Sud</wicri:noRegion><wicri:noRegion>Centre Hospitalier Lyon Sud</wicri:noRegion></affiliation></author><author><name sortKey="Papotti, Mauro" sort="Papotti, Mauro" uniqKey="Papotti M" first="Mauro" last="Papotti">Mauro Papotti</name><affiliation wicri:level="3"><nlm:affiliation>Department of Oncology, University of Turin, 10043, Turin, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Oncology, University of Turin, 10043, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Pilz, Lothar" sort="Pilz, Lothar" uniqKey="Pilz L" first="Lothar" last="Pilz">Lothar Pilz</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, University medical center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Biostatistics, University medical center Mannheim</wicri:regionArea><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Senan, Suresh" sort="Senan, Suresh" uniqKey="Senan S" first="Suresh" last="Senan">Suresh Senan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, VU University Medical Center Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Radiation Oncology, VU University Medical Center Amsterdam</wicri:regionArea><wicri:noRegion>VU University Medical Center Amsterdam</wicri:noRegion></affiliation></author><author><name sortKey="Syrigos, Kostas" sort="Syrigos, Kostas" uniqKey="Syrigos K" first="Kostas" last="Syrigos">Kostas Syrigos</name><affiliation wicri:level="1"><nlm:affiliation>Sotiria General Hospital, Athens School of Medicine, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Sotiria General Hospital, Athens School of Medicine</wicri:regionArea><wicri:noRegion>Athens School of Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Perol, Maurice" sort="Perol, Maurice" uniqKey="Perol M" first="Maurice" last="Pérol">Maurice Pérol</name><affiliation><nlm:affiliation>Department of Medical Oncology, Léon Bérard Cancer Center, Lyon France.</nlm:affiliation><wicri:noCountry code="subField">Lyon France</wicri:noCountry></affiliation></author><author><name sortKey="Gray, Jhanelle E" sort="Gray, Jhanelle E" uniqKey="Gray J" first="Jhanelle E" last="Gray">Jhanelle E. Gray</name><affiliation wicri:level="2"><nlm:affiliation>Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Schabel, Christoph" sort="Schabel, Christoph" uniqKey="Schabel C" first="Christoph" last="Schabel">Christoph Schabel</name><affiliation wicri:level="1"><nlm:affiliation>Department for Diagnostic and Interventional Radiology, Eberhard Karls University Tübingen, University Hospital Tübingen, 72076, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Diagnostic and Interventional Radiology, Eberhard Karls University Tübingen, University Hospital Tübingen, 72076, Tübingen</wicri:regionArea><wicri:noRegion>72076, Tübingen</wicri:noRegion><wicri:noRegion>72076, Tübingen</wicri:noRegion><wicri:noRegion>Tübingen</wicri:noRegion></affiliation></author><author><name sortKey="Van Meerbeeck, Jan" sort="Van Meerbeeck, Jan" uniqKey="Van Meerbeeck J" first="Jan" last="Van Meerbeeck">Jan Van Meerbeeck</name><affiliation wicri:level="1"><nlm:affiliation>Thoracic Oncology/MOCA, Antwerp University Hospital, Antwerp University, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Thoracic Oncology/MOCA, Antwerp University Hospital, Antwerp University</wicri:regionArea><wicri:noRegion>Antwerp University</wicri:noRegion></affiliation></author><author><name sortKey="Van Zandwijk, Nico" sort="Van Zandwijk, Nico" uniqKey="Van Zandwijk N" first="Nico" last="Van Zandwijk">Nico Van Zandwijk</name><affiliation wicri:level="4"><nlm:affiliation>Asbestos Diseases Research Institute, University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Asbestos Diseases Research Institute, University of Sydney, Sydney, New South Wales</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Zhou, Cai Cun" sort="Zhou, Cai Cun" uniqKey="Zhou C" first="Cai Cun" last="Zhou">Cai Cun Zhou</name><affiliation wicri:level="1"><nlm:affiliation>Department of Lung Cancer and Immunology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, People's Republic of China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Lung Cancer and Immunology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine</wicri:regionArea><wicri:noRegion>Tongji University School of Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Manegold, Christian" sort="Manegold, Christian" uniqKey="Manegold C" first="Christian" last="Manegold">Christian Manegold</name><affiliation wicri:level="1"><nlm:affiliation>Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University medical center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University medical center Mannheim</wicri:regionArea><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion></affiliation></author><author><name sortKey="Voigt, Wieland" sort="Voigt, Wieland" uniqKey="Voigt W" first="Wieland" last="Voigt">Wieland Voigt</name><affiliation wicri:level="1"><nlm:affiliation>Medical Innovation and Management, Steinbeis University Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medical Innovation and Management, Steinbeis University Berlin</wicri:regionArea><wicri:noRegion>Steinbeis University Berlin</wicri:noRegion><wicri:noRegion>Steinbeis University Berlin</wicri:noRegion><wicri:noRegion>Steinbeis University Berlin</wicri:noRegion></affiliation></author><author><name sortKey="Roessner, Eric Dominic" sort="Roessner, Eric Dominic" uniqKey="Roessner E" first="Eric Dominic" last="Roessner">Eric Dominic Roessner</name><affiliation wicri:level="1"><nlm:affiliation>Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University medical center Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University medical center Mannheim</wicri:regionArea><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion><wicri:noRegion>University medical center Mannheim</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer</title><idno type="eISSN">1556-1380</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Although the effectiveness of screening for lung cancer remains controversial, it is a fact that the majority of lung cancers are diagnosed at an advanced stage outside of lung cancer screening programs. In 2013, the U.S. Preventive Services Task Force (USPSTF) revised its lung cancer screening recommendation, now supporting lung cancer screening by low-dose computed tomography (LDCT) in patients at high risk. This is also endorsed by many major medical societies and advocacy group stakeholders, however with different eligibility criteria. In Europe, population-based lung cancer screening has so far not been recommended or implemented, as some important issues remain unresolved. Among them remains the open question on how enlarging pulmonary nodules (PNs) detected in lung cancer screening should be managed. This article comprises two parts: a review of the current lung cancer screening approaches, as well as the potential therapeutic options for enlarging PNs, followed by a meeting report including consensus statements of an interdisciplinary expert panel that discussed the potential of the different therapeutic options during the Dresden 2015 Post World Congress of Lung Cancer (WCLC) - International Association for the Study of Lung Cancer (IASLC) meeting.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>France</li><li>Grèce</li><li>Italie</li><li>Norvège</li><li>Pays-Bas</li><li>Pologne</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Floride</li><li>Grand Londres</li><li>Groningue (province)</li><li>Nouvelle-Galles du Sud</li><li>Piémont</li><li>Île-de-France</li></region><settlement><li>Groningue (ville)</li><li>Londres</li><li>Paris</li><li>Sydney</li><li>Turin</li></settlement><orgName><li>Université de Groningue</li><li>Université de Sydney</li></orgName></list><tree><noCountry><name sortKey="Crino, Lucio" sort="Crino, Lucio" uniqKey="Crino L" first="Lucio" last="Crino">Lucio Crino</name><name sortKey="Perol, Maurice" sort="Perol, Maurice" uniqKey="Perol M" first="Maurice" last="Pérol">Maurice Pérol</name></noCountry><country name="Allemagne"><noRegion><name sortKey="Meyer, Mathias" sort="Meyer, Mathias" uniqKey="Meyer M" first="Mathias" last="Meyer">Mathias Meyer</name></noRegion><name sortKey="Buergy, Daniel" sort="Buergy, Daniel" uniqKey="Buergy D" first="Daniel" last="Buergy">Daniel Buergy</name><name sortKey="Giordano, Frank A" sort="Giordano, Frank A" uniqKey="Giordano F" first="Frank A" last="Giordano">Frank A. Giordano</name><name sortKey="Henzler, Thomas" sort="Henzler, Thomas" uniqKey="Henzler T" first="Thomas" last="Henzler">Thomas Henzler</name><name sortKey="Huber, Rudolf Maria" sort="Huber, Rudolf Maria" uniqKey="Huber R" first="Rudolf Maria" last="Huber">Rudolf Maria Huber</name><name sortKey="Kostrzewa, Michael" sort="Kostrzewa, Michael" uniqKey="Kostrzewa M" first="Michael" last="Kostrzewa">Michael Kostrzewa</name><name sortKey="Manegold, Christian" sort="Manegold, Christian" uniqKey="Manegold C" first="Christian" last="Manegold">Christian Manegold</name><name sortKey="Pilz, Lothar" sort="Pilz, Lothar" uniqKey="Pilz L" first="Lothar" last="Pilz">Lothar Pilz</name><name sortKey="Rathmann, Nils" sort="Rathmann, Nils" uniqKey="Rathmann N" first="Nils" last="Rathmann">Nils Rathmann</name><name sortKey="Roessner, Eric Dominic" sort="Roessner, Eric Dominic" uniqKey="Roessner E" first="Eric Dominic" last="Roessner">Eric Dominic Roessner</name><name sortKey="Schabel, Christoph" sort="Schabel, Christoph" uniqKey="Schabel C" first="Christoph" last="Schabel">Christoph Schabel</name><name sortKey="Voigt, Wieland" sort="Voigt, Wieland" uniqKey="Voigt W" first="Wieland" last="Voigt">Wieland Voigt</name></country><country name="Pays-Bas"><region name="Groningue (province)"><name sortKey="Vliegenthart, Rozemarijn" sort="Vliegenthart, Rozemarijn" uniqKey="Vliegenthart R" first="Rozemarijn" last="Vliegenthart">Rozemarijn Vliegenthart</name></region><name sortKey="Dingemans, Anne Marie C" sort="Dingemans, Anne Marie C" uniqKey="Dingemans A" first="Anne-Marie C" last="Dingemans">Anne-Marie C. Dingemans</name><name sortKey="Senan, Suresh" sort="Senan, Suresh" uniqKey="Senan S" first="Suresh" last="Senan">Suresh Senan</name></country><country name="Norvège"><noRegion><name sortKey="Brustugun, Odd Terje" sort="Brustugun, Odd Terje" uniqKey="Brustugun O" first="Odd Terje" last="Brustugun">Odd Terje Brustugun</name></noRegion></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Dusmet, Michael" sort="Dusmet, Michael" uniqKey="Dusmet M" first="Michael" last="Dusmet">Michael Dusmet</name></region><name sortKey="Fennell, Dean" sort="Fennell, Dean" uniqKey="Fennell D" first="Dean" last="Fennell">Dean Fennell</name></country><country name="France"><region name="Île-de-France"><name sortKey="Grunenwald, Dominique" sort="Grunenwald, Dominique" uniqKey="Grunenwald D" first="Dominique" last="Grunenwald">Dominique Grunenwald</name></region><name sortKey="Mornex, Francoise" sort="Mornex, Francoise" uniqKey="Mornex F" first="Francoise" last="Mornex">Francoise Mornex</name></country><country name="Pologne"><noRegion><name sortKey="Moniuszko, Marcin" sort="Moniuszko, Marcin" uniqKey="Moniuszko M" first="Marcin" last="Moniuszko">Marcin Moniuszko</name></noRegion></country><country name="Italie"><region name="Piémont"><name sortKey="Papotti, Mauro" sort="Papotti, Mauro" uniqKey="Papotti M" first="Mauro" last="Papotti">Mauro Papotti</name></region></country><country name="Grèce"><noRegion><name sortKey="Syrigos, Kostas" sort="Syrigos, Kostas" uniqKey="Syrigos K" first="Kostas" last="Syrigos">Kostas Syrigos</name></noRegion></country><country name="États-Unis"><region name="Floride"><name sortKey="Gray, Jhanelle E" sort="Gray, Jhanelle E" uniqKey="Gray J" first="Jhanelle E" last="Gray">Jhanelle E. Gray</name></region></country><country name="Belgique"><noRegion><name sortKey="Van Meerbeeck, Jan" sort="Van Meerbeeck, Jan" uniqKey="Van Meerbeeck J" first="Jan" last="Van Meerbeeck">Jan Van Meerbeeck</name></noRegion></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Van Zandwijk, Nico" sort="Van Zandwijk, Nico" uniqKey="Van Zandwijk N" first="Nico" last="Van Zandwijk">Nico Van Zandwijk</name></region></country><country name="République populaire de Chine"><noRegion><name sortKey="Zhou, Cai Cun" sort="Zhou, Cai Cun" uniqKey="Zhou C" first="Cai Cun" last="Zhou">Cai Cun Zhou</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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